![]() If you give flibanserin, 46% will feel better. So if you give this drug to 100 women, and you give placebo to 100 women, 34 out of 100 of women with placebo will get better, they'll have more interest in sex and they'll have more sexually satisfying sexual activity. Now I want to talk about, if I were going to counsel a patient, what kind of difference was there with flibanserin? So they had this drug and they did a randomized trial where women were given placebo versus this drug at different doses and lo and behold, there was a little difference. Jones: Exactly, and in women it's an internal desire problem.ĭr. Interviewer: Because Viagra solves a mechanical problem.ĭr. So to call this female Viagra is way wrong. They get more blood flow down there but they're not excited. It means you've got desire and it doesn't work and the purple little, blue pill, Viagra, is one of a series of drugs which increase blood flow to the penis, and when you give those kinds of drugs to women, nothing happens. Now, erectile dysfunction is not desire disorder. Guys had a whole menu of things that could work on erectile dysfunction. "Take a couple of drinks and see how you feel." Or, we tried testosterone patches and that's a whole separate issue and that didn't make a big difference, so we really didn't have anything. And for women for whom it causes distress, we have not had anything that works. Those are the two things you have to have. So although not having desire is normal for women, if it was a change in desire and if it causes distress, should we medicate that? My feeling for a patient who comes to me with this complaint, and about 10% of women have this condition, where they have a decrease in their desire and it causes them distress. My husband is looking forward to the kind of closeness we had early in our relationship, the intimacy, frequency, and now, it's not there." My husband is a little tweaked about it, but fine," or, "This has really destroyed our relationship. But then the question you ask is, "How much does this distress you?" and you say, "Well I don't care, it's fine by me. Not being interested in sex isn't a disease. So if I ask women, "Has there been a time in the last year for longer than two weeks when you weren't interested in sex?" Most women are going to respond, "Oh shoot yeah. It's been suggested that as many of 40% of women at some time in their life have a period of time of two weeks when they're not interested in sex. Now, what is this? Is this a disease or do women, when they get to a certain part of life, is not having much of a sex drive perfectly normal and the answer is it's so common, that yes, it's normal. So they decided they'd work on it and see how it really worked in women who complained of hypoactive sexual desire disorder. It increases norepinephrine, another rewards center and it decreases serotonin. So they then went on to say, "We'll take this drug which works on the neurotransmitters in the brain," so this works on dopamine, it increases dopamine, the reward center. But in women it wasn't that great as an anti-depressant, but it actually had a little boost in sexual interest. So they have this drug called flibanserin and they rolled it out, looking at it as an anti-depressant and they found that in men it didn't change their libido one way or the other and it didn't work that great as an anti-depressant. A lot of the drugs in the SSRI group can cause problems with libido. Jones: Sure, what's the pill? Some years ago a drug company in Europe was looking for a new, better anti-anxiety and anti-depressant drug that wouldn't have sexual side effects. So first of all what is this pill and what does it do?ĭr. How would you decide whether or not you would recommend it or not recommend it to a patient? There are benefits, there are drawbacks, the FDA didn't approve it twice and now they've approved it, just a lot of questions. Jones, we've been reading much, as I would imagine our listeners have and seen the news coverage on the little pink pill, it's being called "the female Viagra" which is probably not accurate and we'll talk about that in a second as well. This is the "Seven Domains of Women's Health" with Dr. Kirtly Parker Jones to tell us more about that next on The Scope.Īnnouncer: Covering all aspects of women's health. Interviewer: The little pink pill that helps women's sex drive.
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